HIGHLIGHTS
SUMMARY
Among them, specific (isolated) phobias are the most common anxiety disorders, with a 12-month prevalence of 10.3%, followed by social anxiety disorder (SAD, also called social phobia; 2.7%) and general anxiety disorder (GAD; 2.2%). The authors built anxiety, oxidative stress (OS), nervous system injury (NSI), and Alzheimer`s disease (AD) zebrafish models. The anxiety zebrafish model was established by adding 1(3-chlorophenyl) piperazine hydrochloride (mCPP, 20.0 µg/mL, 1 h incubation at 28◦ C and washed off). The natural amino_acid in green tea (Shanghai Novanat Co. Improved zebrafish . . .
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