O-glcnac impacts mitophagy via the pink1-dependent pathway

HIGHLIGHTS

• What: In the current study, the authors show that OGA inhibition increases mitophagy in SH-SY5Y neuroblastoma cells, C57BL6J mice brains, and organoids differentiated from normal individuals. Ethical approval was not required for the studies on humans in accordance with the local legislation and institutional requirements because only commercially available established cell lines were used.
• Who: Ibtihal M. Alghusen from the Harvard Medical School, United States University of California, Los Angeles have published the paper: O-GlcNAc impacts mitophagy via the PINK1-dependent pathway, in the Journal: (JOURNAL)
• How: The authors showed that . . .
  

   

  

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