O-glcnac-mediated regulation of galectin expression and secretion in human promyelocytic hl-60 cells undergoing neutrophilic differentiation

HIGHLIGHTS

  • who: Adam McTague and collaborators from the Department of Biology, The University of Western Ontario, London, ON N A , Canada have published the Article: O-GlcNAc-Mediated Regulation of Galectin Expression and Secretion in Human Promyelocytic HL-60 Cells Undergoing Neutrophilic Differentiation, in the Journal: Biomolecules 2022, 12, 1763. of /2022/
  • what: The authors show that the hallmarks of all-trans retinoic acid (ATRA)-induced neutrophilic differentiation such as lobular morphology of nuclei , upregulation of genetic biomarkers NCF1 (Neutrophil Cytosolic Factor 1) and NCF2 , and respiratory burst in response to phorbol 12-myristate 13-acetate . . .

     

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