Obese mammary tumour-bearing mice are highly sensitive to doxorubicin-induced hepatotoxicity

HIGHLIGHTS

  • who: Megan Sedeman from the Department of Physiological Sciences, Stellenbosch University, Stellenbosch Campus, Stellenbosch, South Africa have published the research: Obese mammary tumour-bearing mice are highly sensitive to doxorubicin-induced hepatotoxicity, in the Journal: (JOURNAL)
  • what: The aim of this study was therefore to investigate the effects of DXR on hepatic tissue in an tumour-bearing mouse model. Hepatotoxicity: Apoptotic cell death and ALT For the purpose of this study, the authors focussed on the three objectives namely, 1) the effects of obesity on hepatotoxicity, 2) the effects of DXR treatment on hepatotoxicity, and . . .

     

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