HIGHLIGHTS
- who: TYPE et al. from the Karolinska Institutet (KI), Sweden United Kingdom University of Louisville, United States have published the Article: Obesity impacts placental function through activation of p-IRE1a-XBP1s signaling, in the Journal: (JOURNAL)
- what: The authors focused on ER stress and UPR activation in the placenta from a pregnancy complicated with maternal obesity.
- future: Future studies are needed to confirm these findings in_vivo animal studies and explore the value of p-IRE1u03b1 and XBP1s as important biomarkers to predict the adverse pregnancy outcomes (APOs) because of maternal obesity.
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