Obesity-induced chronic inflammation in high fat diet challenged c57bl/6j mice is associated with acceleration of age-dependent renal amyloidosis

HIGHLIGHTS

• who: Roel A. van der Heijden from the DepartmentUniversity Medical Groningen, Groningen, The Netherlands have published the paper: Obesity-induced chronic inflammation in high fat diet challenged C57BL/6J mice is associated with acceleration of age-dependent renal amyloidosis, in the Journal: Scientific Reports Scientific Reports
• what: This study was designed to provide insight into the evolution of both obesity- and age-associated renal pathologies. The authors demonstrate a gradual, age-dependent occurrence of mild albuminuria, tubulo-interstitial and glomerular structural changes, and increased expression of inflammatory mediators.
• how: Data were analyzed using . . .
  

   

  

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