Obesogenic and diabetic effects of cd44 in mice are sexually dimorphic and dependent on genetic background

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  • who: Melissa VerHague from the All procedures were approved by the IACUC at the University of North Carolina (UNC) Chapel HillThree mouse strains were purchased from Jackson Labs: C BL/ J mice (B6) (stock #000664), knockout mice on a C BL/ J background (CD44.B6) (stock #005085), and C H/HeJ mice (C H) (stock #000659). The fourth group of mice was created by selectively backcrossingmice with C H mice for at least , generations resulting in a genotyping-confirmed >, % C H background to result in , knockout on a C H/HeJ background (CD44.C H). For all . . .

     

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