Occurrence and repair of alkylating stress in the intracellular pathogen brucella abortus

HIGHLIGHTS

• who: Katy Poncin from the University of Oxford, South Parks Road, Oxford , RE, UK have published the paper: Occurrence and repair of alkylating stress in the intracellular pathogen Brucella abortus, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
• what: The authors demonstrate that a weak alkylating stress occurs when B. abortus is inside its eBCV in a macrophage cell line. The authors show that XthA1 is the major endonuclease, since its deletion was sufficient to confer sensitivity to MMS, whereas it was not the case for the deletion of xthA2. The authors show that the intracellular . . .
  

   

  

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