Okseqhmm: a genome-wide replication fork directionality analysis toolkit

HIGHLIGHTS

  • who: OKseqHMM a genome-wide replication et al. from the Institut Curie, Universitu00e9 PSL, Sorbonne Universitu00e9, CNRS UMR3244, Dynamics of Genetic Information, Gif-sur-Yvette, France have published the Article: OKseqHMM: a genome-wide replication fork directionality analysis toolkit, in the Journal: (JOURNAL) of May/09,/2022

SUMMARY

    The faithful transmission of genetic_information to daughter cells is crucial for maintaining genome stability. In 2016, Petryk et_al showed that replication fork directionality (RFD) can be directly measured genome-wide by sequencing Okazaki fragments (OK-seq), which are present only on the lagging replicating strand . . .

     

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