Oleic acid from cancer-associated fibroblast promotes cancer cell stemness by stearoyl-coa desaturase under glucose-deficient condition

HIGHLIGHTS

• who: Sung-Hyun Hwang from the College of Veterinary Medicine, Seoul National University, Gwanaku2011Ro, Gwanaku2011Gu, Seoul, Republic of Korea have published the paper: Oleic acid from cancer-associated fibroblast promotes cancer cell stemness by stearoyl-CoA desaturase under glucose-deficient condition, in the Journal: (JOURNAL)
• what: This study investigated that CAFs in xenografted tumors had higher amounts of fatty acids particularly OA compared to normal and promoted the cell stemness in lung adenocarcinoma cells under glucose-deficient condition. This study showed that lipogenesis is activated in CAFs via SCD upregulation under glucose-deficient conditions. The . . .
  

   

  

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