HIGHLIGHTS
- who: from the (UNIVERSITY) have published the paper: Oleuropein aglycone stabilizes the monomeric α-synuclein and favours the growth of non-toxic aggregates, in the Journal: (JOURNAL) of 15/03/2018
- what: The authors show that oleuropein aglycone (OleA), the main olive oil polyphenol, exhibits anti-amyloidogenic power in_vitro by interacting with, and stabilizing, α-synuclein monomers thus hampering the growth of on-pathway oligomers and favouring the growth of stable and harmless aggregates with no tendency to evolve into other cytotoxic amyloids. A first experiment was designed to determine the cytotoxicity of Syn aggregates at different . . .
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