Oligodendroglia-derived extracellular vesicles activate autophagy via lc3b/bag3 to protect against oxidative stress with an enhanced effect for hspb8 enriched vesicles

HIGHLIGHTS

  • who: Bram Van den Broek from the Department of Immunology and Infections, Biomedical Research Institute, Hasselt University, Hasselt, Belgium have published the Article: Oligodendroglia-derived extracellular vesicles activate autophagy via LC3B/BAG3 to protect against oxidative stress with an enhanced effect for HSPB8 enriched vesicles, in the Journal: (JOURNAL)
  • what: The authors show that OL-EVs and modified OL-HSPB8-EVs are internalized by C20 microglia and by primary mixed neural cells. The authors demonstrate that the functions of secreted EVs enriched with HSPB8 have a supu2011 portive role comparable to the native OL-EVs . . .

     

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