HIGHLIGHTS
- who: Thomas A. Nicholson et al. from the University of Birmingham, Birmingham , TT, UK have published the article: Oligonucleotide Therapeutics for Age-Related Musculoskeletal Disorders: Successes and Challenges, in the Journal: Pharmaceutics 2023, 15, 237. of 10/01/2023
- what: With the focus on the tissues of the musculoskeletal system, namely skeletal muscle, cartilage, bone and synovium, the authors evaluate the successes and challenges of oligonucleotide modalities to modulate target gene_expression and ultimately to provide therapeutic efficacy.
- future: Validation of findings from in_vitro studies is needed to evaluate the therapeutic potential of this . . .
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