On the fluorescence enhancement of arch neuronal optogenetic reporters

HIGHLIGHTS

  • who: Leonardo Barneschi from the (UNIVERSITY) have published the research work: On the fluorescence enhancement of arch neuronal optogenetic reporters, in the Journal: (JOURNAL) of 27/05/2022
  • what: The authors demonstrate that a theory can be established by constructing quantum chemical models of a set of Archaerhodopsin reporters in their electronically excited_state. The authors report on a (mechanistic) theory that explains how one-photon FQY is enhanced in Arch3 variants. The authors demonstrate that, to be predictive, such theory requires the mapping of an isomerization path producing a twisted intramolecular diradical intermediate (TIDIR) located . . .

     

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