On the specificity of interaction between the saccharomyces cerevisiae clamp loader replication factor c and primed dna templates during dna replication*

HIGHLIGHTS

  • who: Manju M. Hingorani from the (UNIVERSITY) have published the research: On the Specificity of Interaction between the Saccharomyces cerevisiae Clamp Loader Replication Factor C and Primed DNA Templates during DNA Replication*, in the Journal: (JOURNAL)
  • what: The authors propose that the ability to rapidly bind and release single- and double-stranded DNA coupled with selective, stable binding to primer-template DNA allows RFC to scan DNA efficiently for primed sites where it can pause to initiate clamp assembly. The experiments described below address this question by quantitatively analyzing the interactions between RFC and various . . .

     

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