Oncogenic kras-induced protein signature in the tumor secretome identifies laminin-c2 and pentraxin-3 as useful biomarkers for the early diagnosis of pancreatic cancer

HIGHLIGHTS

  • who: Mohammad Azhar Kamal et al. from the Department of Immunology, Humanitas Clinical and Research Center-IRCCS, Rozzano, ItalyDepartment of Biomedical Sciences, Humanitas University, Pieve Emanuele, Italy have published the article: Oncogenic KRAS-Induced Protein Signature in the Tumor Secretome Identifies Laminin-C2 and Pentraxin-3 as Useful Biomarkers for the Early Diagnosis of Pancreatic Cancer, in the Journal: (JOURNAL)
  • what: The authors report a proteomic signature of KRAS-induced secreted proteins which was confirmed in surgical tumor samples from resected PDAC patients. The authors focused the attention on the proteins secreted by HPDE-E6E7 . . .

     

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