Oncolytic virotherapy: basic principles, recent advances and future directions

HIGHLIGHTS

  • who: Danni Lin from the (UNIVERSITY) have published the Article: Oncolytic virotherapy: basic principles, recent advances and future directions, in the Journal: (JOURNAL) of 20/Oct/2022
  • what: At first, the main focus of reconstructions was to improve target specificity, selective replication and oncolysis. The authors explored the pharmacodynamics of VG161 combined with gemcitabine + nab-paclitaxel in a mouse model of pancreatic cancer, which produced the best effect in the VG161 post-chemotherapy group, while postchemotherapy combined with OVs did not show any gain with OVs benefit compared with monotherapy .
  • future: Future research . . .

     

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