Oncostatin m-enriched small extracellular vesicles derived from mesenchymal stem cells prevent isoproterenol-induced fibrosis and enhance angiogenesis

HIGHLIGHTS

  • who: Sandra Tejedor and colleagues from the , Valencia, Spain have published the research: Oncostatin M-Enriched Small Extracellular Vesicles Derived from Mesenchymal Stem Cells Prevent Isoproterenol-Induced Fibrosis and Enhance Angiogenesis, in the Journal: (JOURNAL) of 30/03/2023
  • what: When injected intraperitoneally into mice treated with isoproterenol OSM-loaded SEVs reduced prevented cardiac hypertrophy and increased Overall the authors demonstrate that the enrichment of functional OSM on the surface of MSC-T-SEVs increases their potency in terms of anti-fibrotic and pro-angiogenic properties which opens new perspectives for this novel biological product . . .

     

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