One cell at a time (ocat): a unified framework to integrate and analyze single-cell rna-seq data

HIGHLIGHTS

  • who: Chloe X. Wang from the University Health Network, Toronto, Canada have published the research work: One Cell At a Time (OCAT): a unified framework to integrate and analyze single-cell RNA-seq data, in the Journal: (JOURNAL)
  • what: The authors propose OCAT One Cell At a Time a machine learning that sparsely encodes single-cell gene expression to integrate data from multiple sources without highly variable gene selection or explicit batch effect correction. The authors demonstrate that OCAT efficiently integrates multiple scRNA-seq datasets and achieves the state-of-the-art performance in cell . . .

     

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