One-pot biosynthesis of 7β-hydroxyandrost-4-ene-3,17-dione from phytosterols by cofactor regeneration system in engineered mycolicibacterium neoaurum

HIGHLIGHTS

  • who: Yun-Qiu Zhao from the State Key Laboratory of Bioreactor Engineering, Newworld Institute of Biotechnology, East China University of Science and Technology have published the research: One-pot biosynthesis of 7u03b2-hydroxyandrost-4-ene-3,17-dione from phytosterols by cofactor regeneration system in engineered mycolicibacterium neoaurum, in the Journal: (JOURNAL)
  • what: This work provided a design concept for engineered strains to produce high-value steroid compounds by microbial transformation in the pharmaceutical industry.
  • how: These results indicated that a 7u03b2-OH-AD producing strain was successfully constructed. The results indicated that . . .

     

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