HIGHLIGHTS
- who: CD, and + T, lymphocytes from the All experiments involving animals were approved by the Animal Ethics Committee of The Institute of Medical Science, The University of Tokyo (A21, have published the paper: OPEN ACCESS, in the Journal: (JOURNAL) of 12/Dec/2022
- what: In the current study, by using ApcMin/+ mice lacking Dok-1/-2 or Dok-3, the authors show that Dok-1/-2 and Dok-3 play distinctive roles in growth and malignant progression of intestinal tumors.
- future: Studies are required for better understanding stromal cell-driven malignant progression and . . .
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