Open access

HIGHLIGHTS

• who: Hiroyasu Konno and colleagues from the (UNIVERSITY) have published the Article: OPEN ACCESS, in the Journal: (JOURNAL) of 13/Dec/2022
• what: The authors report that ZL-1211 is a mAb targeting CLDN18.2 engineered to promote enhanced antibody-dependent cellular cytotoxicity (ADCC) with the goal of achieving more potent activity in a wider spec- cells. The CLDN18.2- or CLDN18.1-overexpressing cells were incubated with ZL-1211 or isotype control Here, the authors report ZL-1211, a humanized monoclonal IgG1 antibody to target not only CLDN18.2-high but also -low gastric . . .
  

   

  

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