Open access

HIGHLIGHTS

• who: Trace M. Jones and colleagues from the All animal studies were performed with the approval of the Institutional Animal Care and Use Committee of the University of Arizona (Tucson, AZ have published the research: OPEN ACCESS, in the Journal: (JOURNAL) of 02/06/2023
• what: The authors demonstrate for the first time that pevonedistat activates antioxidant defense mechanisms selectively in normal kidney cells, which alleviates cisplatin-induced nephrotoxicity while simultaneously improving the anticancer activity of cisplatin against HNSCC cells. Mechanistically, the authors show that this is driven by the differential expression of the pro . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or Email

  Password

  Remember me

  Lost your password?

  If you don't have an account, you can create one here.