Open search-based proteomics reveals widespread tryptophan modifications associated with hypoxia in lung cancer

HIGHLIGHTS

  • who: Jinfeng Chen and colleagues from the Zhengzhou University, Zhengzhou, Henan, China have published the research: Open Search-Based Proteomics Reveals Widespread Tryptophan Modifications Associated with Hypoxia in Lung Cancer, in the Journal: Oxidative Medicine and Cellular Longevity of 30/04/2022
  • what: The authors report a systematic identification of sequence variations at tryptophan termed tryptophan variants from the proteome of patients with nonsmall cell lung cancer (NSCLC). The authors propose that tryptophan variants are associated with oxidative stress induced by reactive species in lung cancer.

SUMMARY

    Proteins are the main . . .

     

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