Open versus closed vitrification system of human oocytes and embryos: a systematic review and meta-analysis of embryologic and clinical outcomes

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  • who: Hongcai Cai from the Libraries, World Health Organization (WHO) International Clinical Trials Registry Platform (ICTRP), Clinicaltrialsgov, and Current Controlled Trials to identify those which assessed embryological and reproductive outcomes by using oocytes and/or embryos vitrified by open or closed devices from women undergoing ART. The following search terms were applied, ‘oocyte', ‘embryo', ‘blastocyst', ‘cleavage-stage embryo', ‘vitrification', ‘cryopreservation', ‘cryosurvival rate', ‘pregnancy rate', and ‘live birth rate', without language restrictions. These searches were limited to human studies. Additionally, relevant studies from the citation list of all retrieved publications and review articles were hand-searched. We contacted . . .

     

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