Opportunities and challenges of alpha-synuclein as a potential biomarker for parkinson’s disease and other synucleinopathies

HIGHLIGHTS

  • who: Pedro Magalhães from the (UNIVERSITY) have published the paper: Opportunities and challenges of alpha-synuclein as a potential biomarker for Parkinson’s disease and other synucleinopathies, in the Journal: (JOURNAL) of 24/06/2022
  • what: Most studies on aSyn levels or PTMs have relied on the use of selected antibodies targeting specific species rather than an unbiased approach aimed at profiling all aSyn species, and in most cases, the antibodies have not been validated for their ability to capture the diversity of modified aSyn species. Because RBCs are considered the major source of . . .

     

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