Opportunities and challenges of targeting c-met in the treatment of digestive tumors

HIGHLIGHTS

  • who: Zhengchao Zhang from the Guangzhou Medical University, China have published the paper: Opportunities and challenges of targeting c-Met in the treatment of digestive tumors, in the Journal: (JOURNAL) of February/28,/2022
  • what: This study found that complications of onartuzumab are also the main reasons limiting its widespread use in clinic.
  • how: The results showed that Sorafenib combined with chemotherapy significantly improved overall survival and had an acceptable toxic effect compared with single Sorafenib treatment. Chenwei Li et_al evaluated the tumorigenicity of PC cells with high expression of c-Met in . . .

     

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