Opposing actions of tlr2 and tlr4 in adipocyte differentiation and mature-onset obesity

HIGHLIGHTS

  • who: Natalia Cuesta and colleagues from the School of Medicine, Universidad Complutense de Madrid, Madrid, Spain have published the Article: Opposing Actions of TLR2 and TLR4 in Adipocyte Differentiation and Mature-Onset Obesity, in the Journal: (JOURNAL)
  • what: At the same time the authors show that TLR2 knock-out mice spontaneously developed mature-onset obesity and insulin resistance. The study showed an increase in the expression of some adipogenic genes in the WAT of TLR2-/- mice.
  • how: The studies in mice show that TLR2 plays a fundamental role in the regulation of adipocyte . . .

     

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