Opposing roles of fact for euchromatin and heterochromatin in yeast

HIGHLIGHTS

• who: Shinya Takahata and Yota Murakami from the Department of Chemistry, Faculty of Science, Hokkaido University, Sapporo, Japan have published the research work: Opposing Roles of FACT for Euchromatin and Heterochromatin in Yeast, in the Journal: Biomolecules 2023, 377 of /2023/
• what: The authors focus on chromatin regulation and gene expression by the yeast FACT complex which functions in both euchromatin and heterochromatin.
• how: This result indicated that a single intrinsic DNA-binding HMGB was not sufficient for intact FACT nucleosome reorganizing activity whereas triple HMGB modules at the Cterminus of Pob3 supported . . .
  

   

  

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