HIGHLIGHTS
SUMMARY
This article aims to summarize the experiments by successfully applying dibenzoyltartaric acid and tartaric acid Na+ -salts as the resolving agents in resolving the two bases starting from their racemic HCl salts. Agent Mixture By preparing sodium salts of the resolving agent, the authors used ((2R,3R)-DBTA·Na and_(R,R)-TA·Na and then performed the resolution, the ((1S,2R)-(+)-EPH) was enriched in the diastereomeric salt. All the solved enantiomeric crystal_structures in the CSD database (EPHECL, EPHECL01, EPHECL02, and EPHECL05 ) exhibit a bit more complex hydrogen_bonds system (involving all NH2 and . . .
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