Optimal sequence-based design for multi-antigen hiv-1 vaccines using minimally distant antigens

HIGHLIGHTS

  • who: Eric Lewitus et al. from the Editor: JDe, Utrecht University have published the research work: Optimal sequence-based design for multi-antigen HIV-1 vaccines using minimally distant antigens, in the Journal: (JOURNAL) of October/31,/2022
  • what: The authors propose a novel vaccine design strategy that integrates the variability observed in acute HIV-1 infections with multiple founder variants. Nonetheless, if datasets of increased depths are available, the model can be used to simulate the multitude of distinct sequences that can be identified in a set of hundreds of Env sequences from acute . . .

     

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