Optimization in chemical modi fi cation of single-stranded sirna encapsulated by neutral cytidinyl/ cationic lipids

HIGHLIGHTS

  • who: Cationic Lipids et al. from the State Key Laboratory of Natural and Biomimetic Drugs, School of Sciences, Peking University, Beijing, China have published the article: Optimization in Chemical Modi fi cation of Single-Stranded siRNA Encapsulated by Neutral Cytidinyl/ Cationic Lipids, in the Journal: (JOURNAL)
  • what: This study provides a safe and efficient ss-siRNA delivery and modification strategy. This study has described a combinational strategy that enables ss-siRNA to exert potent gene silencing activity.
  • how: In this study a homemade oligonucleotides delivery system containing neutral cytidine lipid (DNCA) and cationic . . .

     

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