Optimization of tamoxifen-induced gene regulation in cardiovascular research

HIGHLIGHTS

  • who: Abitha Sukumaran and Sakthivel Sadayappan from the Division of Oncology, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA have published the research: Optimization of tamoxifen-induced gene regulation in cardiovascular research, in the Journal: (JOURNAL) of 30/03/2022
  • what: Although this model has been widely used to temporally control gene_expression at the tissuespecific level, the possible side effects of TAM and/or MerCreMer remain controversial, thus potentially limiting the application of this approac .
  • future: The authors expect that the authors will address these limitations . . .

     

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