Optimized treatment of refractory hypercholesterolemia in patients with atherosclerotic cardiovascular disease or heterozygous familial hypercholesterolemia with alirocumab (optimize)

HIGHLIGHTS

  • who: Isabella Sudano from the Cleveland State University, United States have published the paper: Optimized Treatment of Refractory Hypercholesterolemia in Patients With Atherosclerotic Cardiovascular Disease or Heterozygous Familial Hypercholesterolemia With Alirocumab (OPTIMIZE), in the Journal: (JOURNAL)
  • what: In the present prospective Swiss national-wide cohort study, the authors aimed to investigate the patient profile, efficacy and safety of alirocumab in patients with ASCVD and/or heFH and markedly increased LDL-C despite maximally tolerated statin therapy with or without other lipid-lowering medication used and reimbursed under routine clinical conditions. For the purpose of the . . .

     

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