Optogenetic activation of the diaphragm

HIGHLIGHTS

  • who: Ethan S. Benevides from the University of Florida, Gainesville, Florida, USA have published the research: Optogenetic activation of the diaphragm, in the Journal: Scientific Reports Scientific Reports
  • what: The aim of this experiment was to determine if diaphragm responses to repeated photostimulation were stable over a 1 hour period. The authors demonstrate that an intrapleural microinjection of AAV9 encoding ChR2 can effectively drive ChR2 expression in diaphragm myofibers. When planning for the current study, the authors conducted preliminary experiments in which the authors histologically assessed the mid-cervical spinal cord four months after mice . . .

     

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