Optogenetic-controlled immunotherapeutic designer cells for post-surgical cancer immunotherapy

HIGHLIGHTS

  • who: Yuanhuan Yu from the (UNIVERSITY) have published the article: Optogenetic-controlled immunotherapeutic designer cells for post-surgical cancer immunotherapy, in the Journal: (JOURNAL) of 20/09/2021
  • what: The authors develop far-red light-controlled immunomodulatory engineered cells (FLICs) that the authors load into a hydrogel scaffold, enabling the precise optogenetic control of cytokines release (IFN-u03b2, TNF-u03b1, and IL-12) upon illumination.

SUMMARY

    The resultant wound healing process and perioperative trauma-associated inflammation caused by surgery can promote tumor recurrence, which can result in significant morbidity and mortality . . .

     

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