HIGHLIGHTS
- who: Maria Carolina Gonzalez from the (UNIVERSITY) have published the article: Optogenetic inactivation of the medial septum impairs long-term object recognition memory formation, in the Journal: (JOURNAL)
SUMMARY
Indeed, theta facilitates hippocampal long-term potentiation (LTP), the main cellular model of hippocampus-dependent long-term memory. In rodents, training in an ORM-based learning paradigm activates several plasticity-related signaling pathways and induces LTP in dorsal CA1, indicating that the hippocampus is essential for long-term ORM formation. Septal lesions that impair spatial and working memory do not affect long-term ORM . . .
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