Optogenetic manipulation of calcium signals in single t cells in vivo

HIGHLIGHTS

• who: Armelle Bohineust from the Pasteur, INSERM, Paris, France have published the Article: Optogenetic manipulation of calcium signals in single T cells in vivo, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS of 18/07/2019
• what: As a proof of concept, the authors focused on calcium manipulation, as calcium is a key signaling pathway for many immune cells, including T and B lymphocytes, and several optogenetics strategies based on calcium release-activated channel (CRAC) have been proposed12-16.
• how: Similar results were obtained using individual B3Z clones with a homogenous expression of either . . .
  

   

  

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