Oral cladribine impairs intermediate, but not conventional, monocyte transmigration in multiple sclerosis patients across a model blood-brain barrier

HIGHLIGHTS

  • who: Linda Y. Lin and collaborators from the The University of Sydney, Sydney, NSW, Australia have published the paper: Oral Cladribine Impairs Intermediate, but Not Conventional, Monocyte Transmigration in Multiple Sclerosis Patients across a Model Blood-Brain Barrier, in the Journal: (JOURNAL) of 30/03/2023
  • what: The aim of this study was to determine the transmigratory ability of monocyte and DC subsets in healthy subjects and untreated and cladribine-treated relapse-remitting MS (RRMS) patients using a well-characterised model of the BBB.
  • how: In this model only endothelial cells are used . . .

     

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