Oral proteasomal inhibitors ixazomib, oprozomib, and delanzomib upregulate the function of organic anion transporter 3 (oat3): implications in oat3-mediated drug-drug interactions

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  • who: Yunzhou Fan and colleagues from the Department of Pharmaceutics, Rutgers, The State University of New Jersey, Frelinghuysen Road, Piscataway have published the Article: Oral Proteasomal Inhibitors Ixazomib, Oprozomib, and Delanzomib Upregulate the Function of Organic Anion Transporter 3 (OAT3): Implications in OAT3-Mediated Drug-Drug Interactions, in the Journal: Pharmaceutics 2020, 12, x FOR PEER REVIEW of /2020/
  • what: This study investigated the effects of and delanzomib on the expression and transport activity of and elucidated the underlying mechanisms. COS-7 cells and and HEK293 cells transporters used in the studies will provide the . . .

     

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