Oral transmissibility of prion disease is enhanced by binding to soil particles

HIGHLIGHTS

• who: Christopher J. Johnson et al. from the Program in Cellular and Molecular Biology, University of have published the article: Oral Transmissibility of Prion Disease Is Enhanced by Binding to Soil Particles, in the Journal: (JOURNAL)
• what: The authors assess the oral infectivity of Mte- and soil-bound prions. The authors orally dosed experimental animals with a common clay mineral, montmorillonite, or whole soils laden with infectious prions, and compared the transmissibility to unbound agent. The experiments described above were conducted using the Hyper (HY) strain of hamster-adapted TME agent (PrPHY).
• how . . .
  

   

  

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