Orbitofrontal cortex micrornas support long-lasting heroin seeking behavior in male rats

HIGHLIGHTS

  • who: Mary Tresa Zanda from the Institutes of Health`s Guide for the Care and Use of Laboratory Animals and were approved by Temple University`s Institutional Animal Care and Use CommitteeReagents Heroin hydrochloride was supplied by the National Institute on Drug Abuse drug supply program and was dissolved in, .9% sterile sodium chloride at a dosage ofmg/kg/infusion (high heroin, HH) ormg/kg/infusion (low heroin, HL). miRIDIAN microRNA Rat rno-miR-485-5p mimic, miRIDIAN microRNA Rat rnomiR-485-5p hairpin inhibitor, miRIDIAN microRNA mimic Negative control #, and miRIDIAN microRNA Hairpin Inhibitor Negative Control . . .

     

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