Organoids capture tissue-specific innate lymphoid cell development in mice and humans

HIGHLIGHTS

• who: Geraldine M. Jowett from the College London, London , RT, UK University of have published the research work: Organoids capture tissue-specific innate lymphoid cell development in mice and humans, in the Journal: (JOURNAL) of August/30,/2022
• what: The authors report that the epithelial niche provides critical cues for the maturation of all ILC subsets in parallel, even in the absence of other cell types or microbial tropism, and that gut and lung epithelial_cells drive lasting tissue-specific ILC phenotypes. The authors aimed to assess whether the lack of cytokine expression in HIO-STRO . . .
  

   

  

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