HIGHLIGHTS
- who: Matthew B. Curtis from the DepartmentUniversity of have published the paper: Organotypic stromal cells impact endothelial cell transcriptome in 3D microvessel networks, in the Journal: Scientific Reports Scientific Reports
- what: This study provides new insight into the interplay between stromal cells and endothelial cells at the transcriptomic level in 3D in_vitro models of organotypic vasculature. By culturing the same population of organ-agnostic ECs with OSCs, the authors demonstrate that ECs modulate their transcriptome in response to the specific stromal cell population. By utilizing the same donor source of ECFC-EC for all microvessel . . .
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