Orphan g-protein coupled receptor gprc5b is critical for lymphatic development

HIGHLIGHTS

  • who: Wenjing Xu and collaborators from the Department of Cell Biology and Physiology, The University of North Carolina, Chapel Hill, NC, USA have published the research work: Orphan G-Protein Coupled Receptor GPRC5B Is Critical for Lymphatic Development, in the Journal: (JOURNAL)
  • what: The authors focused on illuminating GPCRs that have enriched expression in human lymphatic endothelial cells compared to human blood endothelial cells. Consistent with the growth restriction and failure to thrive which the authors report here, prior studies also showed that loss of Gprc5b protected mice from diet-induced obesity and insulin resistance . . .

     

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