Oscillations of delta-like1 regulate the balance between differentiation and maintenance of muscle stem cells

HIGHLIGHTS

• who: Yao Zhang from the Center for Molecular Medicine, Berlin, GermanyKyoto University have published the article: Oscillations of Delta-like1 regulate the balance between differentiation and maintenance of muscle stem cells, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
• what: The authors investigate Dll1 expression dynamics in muscle progenitor and stem_cells. The authors show that MyoD and Hes1 directly control Dll1 expression by enhancing and repressing Dll1 transcription, respectively. By restricting the mutation to muscle stem_cells and analyzing their behavior on cultured fibers, the authors show here unambiguously that oscillatory Dll1 produced by activated stem_cells controls . . .
  

   

  

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