Osteoblastic heparan sulfate glycosaminoglycans control bone remodeling by regulating wnt signaling and the crosstalk between bone surface and marrow cells

HIGHLIGHTS

  • who: Corrected Correction et al. from the CNRS, USR3695, Gif-sur-Yvette, France have published the research: Osteoblastic heparan sulfate glycosaminoglycans control bone remodeling by regulating Wnt signaling and the crosstalk between bone surface and marrow cells, in the Journal: (JOURNAL)
  • what: The authors show that syndecan-2 specifically promoted the CD31highEndomucinhigh endothelium in youngest mice.
  • how: To further address this question the authors examined whether syndecan-2 overexpression did modify the endothelium within the bone marrow using CD31 and Endomucin markers to study a pro-osteogenic endothelium that was previously shown to . . .

     

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