HIGHLIGHTS
- who: Masayuki Tsukasaki from the (UNIVERSITY) have published the research: Osteoclast biology in the single-cell era, in the Journal: (JOURNAL)
- how: Intriguingly an analysis of the bone tissue scRNA-seq dataset showed that OPG is highly expressed in the osteoblast subtype characterized by a high expression of an extracellular matrix protein decorin (Dcn) .
- future: Studies are needed to understand the heterogeneity and functional diversity of osteoblasts (Fig 2).
SUMMARY
Since C. H. Robin first depicted a multinucleated cell on the bone surface, early studies using the latest technologies . . .
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