Osteocyte egln1/phd2 links oxygen sensing and biomineralization via fgf23

HIGHLIGHTS

• who: Megan L. Noonan from the Animal studies Animal studies were approved by, and performed, according to the Institutional Animal Care and Use Committee (IACUC) of the Indiana University School of Medicine, and complied with the NIH guidelines for the use of animals in researchC BL/, mice were purchased (Jackson Labs) and acclimated prior to study. Dmp1cre/flox-Fgf, mice were bred in house [57]. Osteocyte-specific deletion of , was obtained by crossing Phd2fl/fl mice, with Dmp1-cre transgenic mice, (Dmp1-Cre+ Phd2fl/fl). Dmp1-Cre- Phd2fl/fl littermates were used as control in all experiments . . .
  

   

  

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