Osteocytes contribute via nuclear receptor ppar-alpha to maintenance of bone and systemic energy metabolism

HIGHLIGHTS

  • who: April and colleagues from the Agricultural University of Athens, Greece have published the paper: Osteocytes contribute via nuclear receptor PPAR-alpha to maintenance of bone and systemic energy metabolism, in the Journal: (JOURNAL) of 16/01/2023
  • what: This study has uncovered the previously unknown contribution of osteocytes to the balance of systemic energy metabolism, in which PPARa plays an important role. The study has confirmed that a KO mice have enlarged bone cavities and presented evidence that PPARa negatively regulates bone resorption on the level of osteoclastic precursor cells and acts as an . . .

     

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